Sugar acids and derivatives
Medchemexpress LLC D-Glucuronic acid | 6556-12-3 | 1 G
D-Glucuronic acid is a key component of anti-inflammatory proteoglycans, promoting embryonic development and inhibiting cell aggregation. When metabolized into ethyl glucuronide, it activates Toll-like receptor 4 (TLR4), contributing to pain. This acid and its derivative, glucurono-lactone, act as liver detoxifiers for human health and show anti-tumor activity.
- Key component of anti-inflammatory proteoglycans.
- Promotes embryonic development.
- Inhibits cell aggregation.
- Acts as a liver detoxifier.
- Derivatives exhibit anti-tumor activity.
- Activates Toll-like receptor 4 (TLR4) when metabolized.
Medchemexpress LLC 4-Methylumbelliferyl 10mM | 440.61 g/mol | C28H40O4 | 10MM 1ML
4-Methylumbelliferyl oleate is a fluorogenic substrate for acid and alkaline lipases 4-Methylumbelliferyl oleate is cleaved by lipases liberating 4-Methylumbelliferyl (Ex/Em 320/450 nm)[1][2]
Alkali Scientific D Glucuronic Acid Sodium Salt Monohydrate, 5 G
D Glucuronic Acid Sodium Salt Monohydrate is a biochemical reagent used in laboratory settings, particularly for carbohydrate and glycobiology research. This 5-gram quantity is ideal for small-scale experiments where glucuronic acid derivatives are required. Glucuronic acid plays a critical role in the metabolism of carbohydrates and lipids, serving as a conjugation agent in the liver for detoxification processes. This chemical is used in the synthesis of glycosaminoglycans and other polysaccharides, making it essential for studies in biochemistry, molecular biology, and pharmaceutical research. The sodium salt monohydrate form ensures enhanced solubility and stability during laboratory use.
Medchemexpress LLC 4-methylumbelliferyl α-L-iduronide | 66966-09-4 | MFCD00135894 | ≥99.0% | 352.29 g/mol | C16H16O9 | 500 UG
4-Methylumbelliferyl α-L-iduronide is a fluorogenic reagent used as a sensitive substrate for α-L-iduronidase and related lysosomal enzyme assays. Enzymatic hydrolysis releases 4-methylumbelliferone, permitting fluorescence-based detection and quantitation in biochemical and cell-based assays.
- Fluorogenic substrate for α-L-iduronidase assays.
- Enables sensitive fluorescence detection and quantitation.
- High purity (≥99.0%) suitable for biochemical applications.
- Available in small research quantities (for example, 500 μg) for assay development.
- Stable solid form for convenient storage and handling.
Medchemexpress LLC Heparin disaccharide I-S tetrasodium | 136098-10-7 | 99.00% | C12H15NNa4O19S3 | 1 MG
Heparin disaccharide I-S tetrasodium is identified as the primary disaccharide resulting from the action of heparinases I and II on heparin. This product is intended for research use only.
- High purity: 99.00%
- Used in biochemical assays
- Supplied as a solid
- Storage at -20°C, sealed and away from moisture
Medchemexpress LLC 4-Methylumbelliferyl 25mg | 18323-58-5 | 440.61 | C28H40O4 | 25 MG
4-Methylumbelliferyl oleate is a fluorogenic substrate used to measure lipase activity; enzymatic hydrolysis liberates 4-methylumbelliferone, a fluorescent reporter (Ex/Em = 320/450 nm). The material is supplied as a 25 mg vial, is soluble in DMSO, and should be stored protected from light at -20°C.
AdipoGen N-Z-L-Homoserine lactone
Chemical. CAS 35677-89-5. Formula C12H13NO4. MW 235.24. N-Z-L-Homoserine lactone is a synthetic building block or intermediate used in the synthesis of biological active agents and analogs of bacterial quorum-sensing signaling molecules. N-Z-L-Homoserine lactone is shown to irreversibly inactivate the 3C cysteine proteinase of hepatitis A virus HAV and might be a scaffold for potent cyteine protein inhibtiors. Shown to reduce the lag phase duration LPD and increase the exponential growth rate EGR of three strains of Pseudomonas fluorescens isolated from refrigerated raw milk.
Medchemexpress LLC Beta-D-glucopyranosyl nitromethane | 81846-60-8 | MFCD08703736 | 99.5% | C7H13NO7 | 10MG
Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane used in chemical research and synthesis. Supplied as a high-purity solid reagent, it serves as a synthetic intermediate, analytical reference, and building block for studies in carbohydrate chemistry and nitroalkane transformations.
- High reported purity for reliable reactions and analyses.
- Water-soluble solid compatible with aqueous and common organic solvents.
- Available in small laboratory pack sizes for flexibility in experimental scale.
- Well characterized with a defined molecular formula for reference.
- Suitable as a synthetic intermediate and analytical reference standard.
Medchemexpress LLC Integrin alpha V bet 100ug | 100ug
Integrin alpha V beta 6 Protein part of the integrin alpha chain family is featured Integrin alpha V beta 6 Protein Rhesus Macaque (HEK293 His) is a recombinant protein dimer complex containing Rhesus Macaque-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Rhesus Macaque (HEK293 His) has molecular weight of 90-140 kDa
Medchemexpress LLC D-Mannoheptulose | 3615-44-9 | MFCD00006622 | 210.18 | 10 MG
D-Mannoheptulose is a 7-carbon keto sugar found in avocado. It is a specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes. This compound can block insulin release and the utilization of carbohydrates in rats. It also exhibits various functions such as antioxidant and anticancer effects, and can act as an energy source.
- Specific inhibitor of D-glucose phosphorylation by hexokinase isoenzymes
- Can block insulin release
- Can block utilization of carbohydrates in rats
- Exhibits antioxidant effects
- Shows anticancer effects
- Acts as an energy source
- Inhibits breast cancer cell line growth (MCF-7 IC50: 263.3 μg/mL)
- No significant cytotoxic effect on normal cells (HMECs IC50: 975.1 μg/mL)
Medchemexpress LLC Rose-β-D-Gal | 138182-21-5 | MFCD01310928 | 99.7% | 329.73 g/mol | C14H16ClNO6 | 10 MG
Rose-β-D-Gal is a chromogenic substrate for β-galactosidase that produces a pink/magenta color upon enzymatic cleavage. It exhibits fluorescent properties (excitation 488 nm and emission 540 nm), is supplied as a white to off-white solid, and is intended for biochemical and cell-based assays to detect β-gal activity.
- Chromogenic substrate for β-galactosidase detection.
- Produces a pink/magenta color upon enzymatic cleavage.
- Excitation 488 nm and emission 540 nm for fluorescence-based assays.
- High purity suitable for analytical and research applications.
- Solid form for easy weighing and storage.
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 10MG
Medchemexpress LLC Integrin alpha 8 bet 100ug
Integrin -8/ -1 coordinates the recruitment of mesenchymal cells during renal organogenesis and recognizes RGD sequences in ligands such as TNC FN1 SPP1 TGFB1 TGFB3 and VTN It plays a role in multiple cellular interactions critical for organogenesis including NPNT as a functional ligand in nephrogenesis Integrin alpha 8 beta 1 Protein Human (HEK293 His) is a recombinant protein dimer complex containing human-derived Integrin alpha 8 beta 1 protein expressed by HEK293 with C-His labeled tag Integrin alpha 8 beta 1 Protein Human (HEK293 His) has molecular weight of 120-140 kDa 100-120 kDa respectively
Medchemexpress LLC Integrin alpha 5 bet 10ug
ITGA5 is a multifunctional receptor that interacts with multiple ligands such as fibronectin fibrinogen PLA2G2A fibrillin-1 (FBN1) IL1B human metapneumovirus and soluble CD40LG ITGA5 recognizes RGD sequences and mediates cell adhesion through different binding sites Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) is a recombinant protein dimer complex containing human-derived Integrin alpha 5 beta 1 protein expressed by HEK293 with C-Flag C-10 His labeled tag Integrin alpha 5 beta 1 Protein Human (HEK293 Flag-His) has molecular weight of 101 35 kDa